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Introduction Taenia solium is the causative agent
2020-02-17

Introduction Taenia solium is the causative agent of human taeniasis/cysticercosis and porcine cysticercosis, a major health problem and a veterinary economic challenge in developing countries of Latin America, Africa, and Asia. In Mexico, approximately 500 human neurocysticercosis cases were repor
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Despite a high affinity for progesterone and a
2020-02-17

Despite a high affinity for progesterone and a relatively high affinity for testosterone [7], the binding of progesterone and testosterone to CBG is often disregarded [1], [2], [3]. However, the concentrations of these two hormones varies considerably under both normal physiological and pathophysiol
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The role of activation of xenosensor nuclear receptors
2020-02-17

The role of activation of xenosensor nuclear receptors such as PPARα, CAR, and PXR in producing hepatomegaly and liver tumors in rodents has been well-established (Klaunig et al., 2003, Lake, 2009). In the case of PPARα, the increase in liver weight results from increased peroxisomal mass and expans
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In conclusion using human liver microsomes supersomes from b
2020-02-17

In conclusion, using human liver microsomes, supersomes from baculovirus-transformed insect cells expressing different human CYP450 isoforms, and V79MZh3A4 cells, MB2 and MB4 were formed from TRB and MC from TRC. The amounts of MB2, MB4, and MC formed were related to the 6β-testosterone hydroxylase
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br DGAT proteins lipid droplets and cancer cells br
2020-02-15

DGAT proteins, lipid droplets and cancer cells Conclusions and future directions Conflicts of interest Acknowledgements This work was supported by NIH grants GM062887, P01CA097132, and Veterans Affairs Merit Award to LMO. Introduction Bioethanol and biodiesel are regarded as the two
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Where does this transfer process occur The maternal
2020-02-15

Where does this transfer process occur? The maternal side of the placenta is textured and spongy looking. The surface has 20–30 distinctive compartments named cotyledons, inside of which are the chorionic villi that form the principal functional structural unit of the placenta. These villi are compl
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CellProfiler and OpenComet are two open source software
2020-02-14

CellProfiler and OpenComet are two open source software available in internet to analyse silver stained comet assay images. With CellProfiler [19], Gonzalez et al. [18] modified the pipeline provided in the website by adding a background subtraction module and two filtering modules to quantify DNA d
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In conclusion we have discovered two new
2020-02-14

In conclusion, we have discovered two new derivatives ( and ) that are potent inhibitors of DHODH. H and C NMR spectroscopic data revealed that these compounds undergo ready isomerisation at room temperature in -DMSO, but the docking studies indicate that there is neither conformation nor configurat
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Furthermore we found that expression of
2020-02-14

Furthermore we found that expression of two C1 nodule cysteine proteases, Glyma.06G283100 and Glyma.06G174800, changed very little under drought despite the two proteases having similarity to the Arabidopsis senescence-related SAG12 gene with 62% similarity by Glyma.06G283010 and 58% by Glyma.06G17
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tranylcypromine The intricate roles and neural
2020-02-14

The intricate roles and neural systems and mechanisms involved in the CRF1 and CRF2 mediation of spontaneous and stress-induced anxiety behavior remain to be defined. Of particular relevance are studies evaluating the behavioral actions of CRF1 and CRF2 receptors separately as well as together. For
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br Conclusions Taken together a distinct contrast is
2020-02-14

Conclusions Taken together, a distinct contrast is observed between ERK1/2 phosphorylation in hypothalamic and extra-hypothalamic SU 9516 mg regions. The hypothalamus is the only brain region where ERK1/2 phosphorylation was increased 15minutes after the OF stressor. In SD rats CRFR1 expression
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Pahlavanzadeh and Fakouri Baygi employed PC
2020-02-14

Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the Calyculin A of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was achieved equal
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Although the control group and tinnitus group do not signifi
2020-02-14

Although the control group and tinnitus group do not significantly differ based on age, gender or hearing loss, a limitation of this study is that the control group is only group-matched, and not individually matched. Furthermore, we only tested hearing acuity in tinnitus patients via standard pure
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Diabetic retinopathy is a chronic inflammatory disease Local
2020-02-14

Diabetic retinopathy is a chronic inflammatory disease. Local inflammation plays a pivotal role in the pathological development and progression of this disease [24]. In addition to TNF-α, several other cytokines, chemokines, and other factors such as IL-1β, IL-6, and C-reactive protein have been ind
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br Results br Discussion Repair by NHEJ implicitly requires
2020-02-13

Results Discussion Repair by NHEJ implicitly requires the pairing together of broken chromosome ends. A complex of Ku, XRCC4, DNA ligase IV, and XLF (PEC) is necessary and sufficient for this purpose (Reid et al., 2015). Here, we describe dynamic changes in this complex that are triggered by d
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